Research
Intra-tumour heterogeneity emerges as a consequence of co-evolving genomes and transcriptomes interacting with a dynamic environment. Conveniently, cancer cells accumulate genetic mutations over time that can be used as naturally occurring barcodes. They provide windows into the evolutionary histories of tumours and at least partially predict treatment outcomes. My research interest lies in deciphering patterns of intra-tumour heterogeneity using mathematical and computational methods. Recently, I caught specific interest in inferring phenotypic plasticity and lineage reconstruction from somatic mutations in mitochondrial DNA.
Biography
I started my Postdoc in the labs of Maxime Tarabichi (IRIBHM-ULB) and Jonas Demeulemeester (VIB-KU Leuven) in June 2025, where my research focus will be on the spatio-temporal dynamics of genome and transcriptome in tumours. Previously, I did my PhD under supervision of Benjamin Werner (BCI-QMUL) and Kateřina Staňková (TU Delft) with a dissertation titled 'Mathematical modelling of tumour evolution: From intra-tumour heterogeneity to treatment resistance'. Before that, I did my BSc and MSc in phyiscs (ETHZ).
