Research
I started my PhD in the fall of 2024 under the supervision of Maxime Tarabichi. The project is about understanding the molecular mechanisms associated with thyroid cancer development. For this purpose, I will study organoid models that are being developed by my colleagues at the institute. In these models, the BRAFV600E mutation is induced after the thyroid follicles have matured. This mutation is the most common driver mutation in human papillary thyroid carcinomas. Our plan is to apply single-cell and spatial RNA sequencing to characterize the new organoid model. In order to study the growth of the malignant cells, I will write a lineage tracing tool that bases its phylogenetic inference procedure on the mutations occurring in the mitochondrial DNA.
Biography
I completed by bachelor’s studies in computer science at the Vrije Universiteit Brussel, during which I interned at Intersystems as a sales engineer. Then I completed a master’s in bioinformatics and modelling at the Université Libre de Bruxelles, during which I spent a semester at National Yang Ming Chiao Tung University, Taiwan as an exchange student. I also interned at Sciensano for two months, making a bioinformatics pipeline for bacterial genomics. My master thesis was about informing individual-based epidemiological models with virus genome sequences.
Publications
No publications found.
