Computational Biology Labs @ IRIBHM

Valeriia Gulaia
Postdoc
🦠

Research

Currently, I am working with Vincent Detours and Maxime Tarabichi on performing spatial transcriptomics on Illumina flow cells with tissue fixed in PaxGene. This project is challenging as it demands specific knowledge that I never had before, such as how to engrave or cut the glass, 3D-printing of tools for pipetting, choosing polymeric material sustaining high temperature and still having good thermal transduction, and so on. I have started my position in the February 2023 and now, one year later, I have learned exorbitant number of things which are very far from molecular biology (including a little bit of bioinformatics and a tiny bit of French language), and this is something that makes me feel good about my work.If you want to know more about spatial transcriptomics with a new non-commercial approach, please connect me!

Biography

Hello, my name is Valeriia, and I am a postdoc at the Computational Biology Lab in IRIBHM. I am originated from Kazakhstan (Karaganda), but all my high education I obtained in Russia starting from Medical Biochemistry in Siberian State Medical University (Tomsk) and finalizing with PhD degree in biology at Far Eastern Federal University (Vladivostok). In between I also received master’s degree in biomedical sciences at the University of Maastricht (Netherlands), where I was testing the efficacy of a bispecific antibody in inducing immune response against breast cancer.My PhD project was investigating the broad molecular effect of the two single nucleotide mutations in brain tumours (gliomas). During my PhD I had opportunities to go abroad to learn very interesting methods as single nucleus transcriptomics in the University of Copenhagen (Denmark) and CRISPR/Cas9-editing by deamination with base-editors in the Dresden University of Technology (Germany)

Publications

The Extracellular Matrix and Biocompatible Materials in Glioblastoma Treatment β€” Frontiers in Bioengineering and Biotechnology, 2019